20200202 Day 33: First Palindrome Date since 11/11/1111

I prefer to write my dates in YYYYMMDD format. It makes sense to me from a general-to-specific way of thinking and it also is numerically sorting friendly (at least until 10000/01/01). Whether using YYYYMMDD format, MM/DD/YYYY format, or DD/MM/YYYY format, today’s date of 02/02/2002 is a palindrome. The last time this was true was 11/11/1111, which coincidentally was 909 years ago – also a palindrome number. There’s a third coincidence which is this day of the new year is day number 33 – also a palindrome number.

A palindrome is a word, phrase, or sequence that is the same when read backwards or forwards. For a parallel worlds viewpoint, palindromes are like portals to a completely different set of universes in which words or sequences are written in the opposite manner. This is because the palindrome is the same in both sets of universes even if many other things are likely to be very different. So in a universe where we count:

1,2,3,4,5,6,7,8,9,01,11,21,31,41,51,61,71,81,91,02

Then 33 and 909 are both written the same. Notice though that in these backwards number universes, the year would be 0202 and the month/day would be 20/20, so the date would actually be written differently (20/20/0202). It would still be a palindrome and still be the first palindrome in 909 years.

Palindromic sequences are also found in nature. Coronaviruses are positive-sense RNA viruses. After the SARS epidemic in 2002, researchers began studying the genome sequence of the then called “novel coronavirus”. One article, Palindromes in SARS and Other Coronaviruses, reported on a study of the collective counts of palindromes in the SARS genome compared with other coronaviruses. The researchers found that while length-four palindromes were underrepresented in coronaviruses as a group, the SARS genome was the only coronavirus to be significantly underrepresented in length-six palindromes. The abstract also noted:

Two other features are unique to the SARS sequence. First, there is a length-22 palindrome TCTTTAACAAGCTTGTTAAAGA spanning positions 25962-25983. Second, there are two repeating length-12 palindromes TTATAATTATAA spanning positions 22712-22723 and 22796-22807. Some further investigations into possible biological implications of these palindrome features are proposed.

Notice that the palindromic sequence is a matching nucleotide in reverse, so that TCTT is a palindrome for (read in reverse) AGAA. I just did a blast search of the length-22 palindromic sequence and found many hits – the vast majority were for SARS coronavirus sequences. One of these, Bat SARS-like coronavirus WIV1 (ID: KF367457.1), I noticed was also in an science mag article:

image.png

A blast alignment of Bat SARSr-CoV WIV1 with the Wuhan seafood market pneumonia virus (MN908947.3) showed a 78% sequence identity.

I more recent article, Complemented Palindromic Small RNAs First Discovered from SARS Coronavirus, mentions this same 22-bp DNA complemented palindrome sequence as one in which a 19-nt cpsRNA (complementary palindromic small RNA) sequence was found (UUAACAAGCUUGUUAAAGA) named SARS-CoV-cpsR-19. This paper reported results which suggested, along with past research, that this small RNA plays a role in SARS-CoV infection or pathogenesis. An image from this article helps to show why these complementary palindromic small RNA sequences are important:

Screen Shot 2020-02-02 at 2.56.52 PM.png

2020 Day 32: The 32 Paths of Wisdom

To finish the story from 2020 Day 31 Addendum 1: The washer looks damaged, my brother decided to be in the universe where he had a washing machine, even though it was dented. This did result in him getting a 10% discount.

For this day 32, I felt a universe where I talk about math, binary numbers, base 32 numbers, and counting to 32 with one hand. I also felt a universe where I wrote about the 32 Paths to Wisdom. I’m leaning towards the second universe …

 

2020 Day 31 Addendum 1: The washer looks damaged

I just posted my Day 31 post 2020 Day 31: Delivering a washing machine through the multiverse with an ending comment:

From what I know about universe surfing and parallel universe interference, I suspect that there are more interesting universe collisions to come around this series of events.

I just heard from my brother, relaying a quote from the delivery guy:

The washer looks damaged

More universe surfing to come …

2020 Day 31: Delivering a washing machine through the multiverse

As I’m typing this, a Low’s truck with a new clothes washer is heading to my brother’s house. Originally, the delivery was scheduled for yesterday. However, my brother had received a letter in the mail stating that the mountain road was going to be closed most of the day. It ended up remaining open all day and had my brother not read the letter, the washing machine would have already been delivered.

Since then we have been looking at different options to take my brother and family to the airport with all of their luggage. We explored lots of different options. At one point one of their cars was going to be parked at a friend’s house near the airport. At another point two cars would be parked there. Now we are in a universe where no cars will be parked there. I just found out that the delivery truck is running ahead of schedule  and so my brother decided to delay his trip to the airport rather than have me drop him off return before the delivery.

Once the delivery truck gets here, there will be some more decisions to be made. The route to take for removing the old washing machine and moving the new one into place. Last night we measured different routes and finally found one that looks like an interference pattern of the other routes that were not ideal for one reason or another.

The replacement of the washing machine was a last minute decision when the current washing machine broke a few days ago. A family with 4 kids is renting my brother’s house for a month and they had previously told my brother how happy they were that there was a washing machine. So, leaving with a broken washing machine was not an option.

Renting to the family with 4 kids was also a last minute decision. The house had been offered for rent with no takers and I was planning to house sit it for part of the time they were gone. As he was taking the ad down, the family with 4 kids notified him that they wanted it.

From what I know about universe surfing and parallel universe interference, I suspect that there are more interesting universe collisions to come around this series of events.

2020 Day 30: Needs that Healers Have – Determining Market Value

In 2020 Day 28: Helping Healers determine what to charge for their offerings, I discussed how to determine what to charge for products and services. I presented a couple of equations:

Cost of Product/Service < Price of Product/Service < Price Customer Will Pay

Price Customer Will Pay < Customer’s Perceived Value

I also noted that it can be difficult to determine the customer’s perceived value of a healer’s offering. If measured by the benefit to the customer, the value could be unbounded in many cases. However, often customers use the price of similar offerings to create a perceived value without considering the actual value to the customer. For instance, if a customer can find multiple places offering $50 one-hour massages, then they may come to perceive the value of a one-hour massage at $50.

A different way to determine a customer’s perceived value is to give customers a coupon for any one of a group of products and/or services and see which one they pick. With enough coupons, this will give you relative values of your products and/or services.

A third way is to just ask your customers how much they value your offerings. Understand the non-monetary value in as much detail as possible. From this you may be able to find competing offerings that would give the customer the same non-monetary values.

If your offering requires your customer to commit a certain amount of their time, then you need to factor in how much your customer values their time. Imagine a customer who makes $100/hr after taxes. Then they are already spending $100 of their time for a one-hour massage.  Whether they consider this consciously or not, these customers will normally be less price sensitive than someone who values their time at only $25/hr after taxes. This is not just a factor of the amount of disposable income each person has. It is related to how much they value their time.

The perceived scarcity of your offering will greatly affect its perceived value. If your offering is seen as a commodity, then it will have a value similar to that commodity. If your offering is seen as one-of-a-kind, then its value is determined by your offering price and the demand from customers who can afford your price.