Y is for Tyrosine, aka 4-hydroxyphenylalanine, a non-essential amino acid with a polar functional group. Tyrosine was first discovered in the cheese protein casein and was named after the Greek word for cheese, tyrós.
Tyrosine is encoded by the two codons UAC and UAU. Tyrosine is often substituted with the similar but essential amino acid Phenylalanine, encoded by the nearby codons UUC and UUU. Humans can synthesize Tyrosine from Phenylalanine.
Tyrosine is a precursor to neurotransmitters Dopamine, neurotransmitter and hormone Noradrenaline, hormone Adrenaline and the pigment Melanin.
Tyrosine is decarboxylated to tyramine in the gut and also during fermentation. Tyramine can cause blood vessels to constrict, increase blood pressure, and also cause heart palpitations. Foods high in tyramine include fermented vegetables, wine and beer, aged cheese, cured meats, chocolate, coffee, soy sauce, and salt-dried fish (ref: https://www.ncbi.nlm.nih.gov/books/NBK563197/).
In proteins, the Tyrosine residues may by phosphorylated by tyrosine kinase enzymes. This phosphorylation can change the function or location of the protein. Tyrosine kinases are important for maintaining normal cell growth and differentiation. Tyrosine kinase disfunction can lead to carcinogenesis. For this reason, targeted tyrosine kinase inhibitors are used in treating cancer. Resistance to these inhibitors is being studied (https://doi.org/10.1038/s41392-022-01168-8).
Regarding the exit of the wormhole that I felt 20 days ago, I can report feelings of humbleness and WTF. I’m still processing what happened around midnight on the 21st of Dec. There was definitely an extreme shift and completely unexpected experience. I wonder how much of it was brought on by my anticipation of a wormhole exit. I did share with AZ that I was expecting a shift and so perhaps her behavior was impacted. Most of the differences I feel are internal versus external. However, these internal changes seem to be impacting my external reality.